top of page

Just a Curse Word? Nope!

What is MTHFR? A swear word? Kind of but not really. I think of it as the mother f*!#$@ gene because that's what most people feel, and sometimes even say, when they find out they have it.

In this post you will learn what the MTHFR gene is, it's function, signs of a mutation on this gene, how to test for it, and natural treatments to manage this mutation.

MTHFR GENE: The human body is made up of trillions of cells. Inside each cell is our DNA that provides instructions for how our body functions. Genes are a segment of the DNA and one of these segments is the MTHFR gene. This gene is in every cell and affects almost every function of our body.

MTHFR FUNCTION: Most simply put, the MTHFR gene is responsible for conversion. The main role of the MTHFR gene is to convert folic acid into the usable form folate or methylfolate (the best form of it). If there is a mutation on this gene, the ability to convert and use what is ingested is compromised. If methylfolate can not be made it impacts other body systems and enzymatic reactions such as SAMe (compound found naturally in the body to help regulate hormones and cell membranes; use under the guidance of a healthcare professional). This begins a vicious cycle. If the body doesn't have a proper methylation process it causes other issues. One of these is an increased homocysteine level, which causes inflammation. When homocysteine is elavated it impairs the bodies ability to produce methyfolate and process glutathione (powerhouse antioxidant). If glutathione can't be produced the cells are more effected by oxidative stress and free radicals. When glutathione and SAMe are affected the immune system, cellular repair, inflammatory response, and detoxifation process is impacted.


  • Infertility

  • Miscarriages

  • Pre-eclampsia

  • Mood imbalances such as depression and anxiety

  • Schizophrenia

  • ADHD

  • Elavated homocysteine levels

  • Digestive issues, including IBS (Irritable Bowel Syndrome)

  • Hormonal issues, including PCOS (Polycystic Ovary Syndrome)

  • Autoimmune disease and thyroid issues

  • Cardiovascular disease

  • Chronic Fatigue

  • Migraines


1) A test can be ordered through 23andme

2) Ask your healthcare provider

* It's ideal to work with a professional to ensure you request raw data


  • Ea